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KMID : 1103720080590040225
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Journal of the Korean Society of Radiology
2008 Volume.59 No. 4 p.225 ~ p.234
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The Diagnostic Accuracy of the 64-slice Multi-detector CT Coronary Angiography for the Assessment of Coronary Artery Stenosis in Symptomatic Patients
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Ko Sung-Min
Nam Chang-Wook
Kim Dong-Hun
Yi jeong-Geun
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Abstract
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Purpose: We evaluated the diagnostic accuracy of a 64-slice multi-detector CT (MDCT) coronary angiography against a conventional coronary angiography (CCA) for the detection of significant stenosis (≥50% lumen diameter narrowing).
Materials and Methods: Sixty-four patients underwent a MDCT and a subsequent CCA to evaluate the presence of atypical chest pain or suspected coronary artery disease (CAD). A MDCT angiography was performed using a 64-slice MDCT-scanner (Sensation 64, slice collimation 32x0.6 mm). The coronary artery segments were classified according to a 15-segment model. The sensitivity, specificity, and diagnostic accuracy of the 64-slice MDCT for the detection or exclusion of significant CAD were calculated on a per-segment and per-patient basis.
Results: Fifty-nine of the 64 (92%) coronary CT angiograms were of diagnostic image quality with 93.5% (809 of 865) of the coronary segments assessable by CT angiography. One-hundred two (12.6%) segments showed significant stenosis by CCA. Stenosis of 50% or greater was detected by sensitivity, specificity, accuracy, positive predictive valve, and negative predictive value on a per segment basis (89%, 99%, 97%, 90%, and 98%, respectively) and a per-patient basis (96%, 69%, 90%, 92%, and 82%, respectively).
Conclusion: The 64-slice MDCT coronary angiography demonstrated a high diagnostic accuracy for both the per-segment and per-patient analyses for this symptomatic patient group.
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KEYWORD
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Computed tomography (CT), Coronary angiography, Coronary vessels, CT, Coronary vessels, stenosis or obstruction
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